Proving HIV-1 immunity: new tools offer new opportunities

Proving HIV-1 immunity: new tools offer new opportunities.

New Tools for Proving Dualizability

We address the problem of proving that a finite algebraM is dualizable, or strongly dualizable, in the sense of [1]. There are generally two aspects to the problem: (1) handling the finite members of SP(M), and (2) handling the infinite members of SP(M). In principle, the problem rests entirely at the infinite level (that is, in the second aspect). In practice, however, the real work is typical...

Changing technologies offer new opportunities in the plant sciences1

The plant sciences are now facing an unprecedented time in our history in which technology is advancing at a rapid pace, creating a wide variety of novel opportunities for our field. Applications in Plant Sciences is a new source for sharing exciting and innovative applications of new technologies that have the potential to propel plant research forward into the future.

Surveillance for incident HIV infection: new technology and new opportunities.

Although surveillance for HIV infection has traditionally focused on the incidence of AIDS and the prevalence of HIV, new diagnostic technologies that allow the estimation of incident HIV infection have become available. Number and distribution of new cases of HIV infection, rather than old cases, are the data most relevant to guide rational application of HIV prevention programs. Historically,...

New macrophage models of Gaucher disease offer new tools for drug development.

Gaucher disease is an inherited enzyme deficiency resulting in the lysosomal accumulation of specific glycolipids in macrophages and, in some cases, neurons. While current treatments are effective at reducing this glycolipid storage in macrophages, they are expensive and ineffective in treating neurological manifestations of the disease, driving the search for novel therapeutics. Moreover, muta...